Effects Of Aqueous extract Of Tamarindus indica on body weight and Liver function of Wistar Rats
- By Dennis Amaechi, G.S. Ntia, I.P. Ekpe, B.N. Yisa - 08 Dec 2022
- Journal of Agricultural and Food Chemical Engineering, Volume: 2, Issue: 1, Pages: 19 - 22
- Received: 18 November 2021; Accepted: 5 February 2022; First Online: 30 March 2022
This study aims at investigating an impacts of ethanolic extracts of Tamarindus indicaon liver biomarkers such as Aspartate transaminase, Alkaline phosphatase, Alanine transaminase, and body weight (bw) of Wistar rats. Species have been classified into four groups. Normal handling cluster A received rat feed and water ad libitum only, Test Group B (100 mg/kg bw), Test Group C (150 mg/kg bw) and Test Group D (200 mg/kg bw) of the aqueous Tamarindus indica respectively. The management of a harvest has been done twice everyday (morning and evening) for a period of seven (7) days. The activity of liver function was assessed by quantifying the alterations in the serum liver enzyme levels. Data was analysed by One-way ANOVA and significance was considered at (p<0.05). The two dose levels of Tamarindus indica fruit extract significantly lowered the levels of the liver enzyme biomarkers (AST, ALT and ALP) and there were no significant changes in the weight of the rats. Present study showed that Tamarindus indicamay possesses hepatoprotective potentials and for maintenance of body weight.
Keywords: Hepatoprotective potentials, Biomarkers, Enzymes, Body weight