Healthcare Studies

Research Article

Haematological and Biochemical Viability of Stored Whole Blood, Packed Red Cells and Fresh Frozen Plasma

  • By Goodnews Nkabari Nwika, Stella U Ken-ezihuo, Evelyn Mgbeoma Eze - 18 Jan 2024
  • Healthcare Studies, Volume: 2, Issue: 1, Pages: 1 - 8
  • https://doi.org/10.58612/hs211
  • Received: November 10, 2023; Accepted: January 7, 2024; Published: January 18, 2024

Abstract

Aim: This study aimed at evaluating the haematological and biochemical viability of whole blood, packed red cells and fresh frozen plasma under storage. Methods: This study adopted the venipuncture blood collection method, sedimentation method for components preparation and the manual, automated and enzymatic method for analysis. Data obtained were statistically analyzed using ANOVA, descriptive analysis, frequency distribution, and mean standard deviations with a statistical significance set at P < 0.05. Results: The result showed (1.6, 3.7, and 4.5) × 109/L and (56.1, 86.0, and 135.9) × 109/L WBC and platelets reduction, in whole blood (WB), packed red cells (PRC) and fresh frozen plasma (FFP), respectively. There occurred a RBC and HCT reductions of (0.8 and 4.1) × 1012/L and (4.6 and 39.5) % in whole blood (WB) and FFP, respectively. Also, a 6.8 g/dL increase in Hb. No significant difference was observed in MCH and MCHC in whole blood and PRC. An ANOVA analysis revealed a pH stability in the fresh frozen plasma, 9.4 mmol/L decrease in sodium and 7.9 mEq/L increase in potassium in PRC.